DeMAND

DOI: 10.18129/B9.bioc.DeMAND    

This package is for version 3.9 of Bioconductor; for the stable, up-to-date release version, see DeMAND.

DeMAND

Bioconductor version: 3.9

DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.

Author: Jung Hoon Woo <jw2853 at columbia.edu>, Yishai Shimoni <ys2559 at columbia.edu>

Maintainer: Jung Hoon Woo <jw2853 at columbia.edu>, Mariano Alvarez <reef103 at gmail.com>

Installation

To install this package, start R (version "3.6") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DeMAND")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DeMAND")

 

PDF	R Script	Using DeMAND
PDF		Reference Manual
Text		LICENSE

Details

biocViews	GeneExpression, Network, NetworkEnrichment, Software, StatisticalMethod, SystemsBiology
Version	1.14.0
In Bioconductor since	BioC 3.2 (R-3.2) (4 years)
License	file LICENSE
Depends	R (>= 2.14.0), KernSmooth, methods
Imports
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Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	DeMAND_1.14.0.tar.gz
Windows Binary	DeMAND_1.14.0.zip
Mac OS X 10.11 (El Capitan)	DeMAND_1.14.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/DeMAND
Source Repository (Developer Access)	git clone [email protected]:packages/DeMAND
Package Short Url	https://bioconductor.org/packages/DeMAND/
Package Downloads Report	Download Stats